07. October 2017
Polymer based dosages form the mainstay of drug delivery systems either as simple matrix carrier materials or active release behaviour modulating agents. In addition, several techniques have been developed further to deliver novel polymeric structures. One such method is electrospinning (ES); a maturing process which is operational at the ambient environment and enables drug loading (in molecularly dispersed form) directly into a fibrous polymer matrix system. Since there is an impending need...
24. September 2017
Objective: The aim of present study was to prepare and evaluate the trans- dermal lms (TFs) of Nifedipine (NFDP). Methods: The TFs were prepared by solvent evaporation technique and twelve formulations of NFDPTFs were prepared by taking HPMC E15 and Eudragit L100 in different ratios. Polyethylene glycol (15%) and Dimethyl sulfoxide (DMSO) were incorpo- rated as plasticizer and permeation enhancer respectively. DMSO was in- corporated in the formulations F7-F12 but it was absent in F1-F6....