04. June 2018
Complex hydrogels formed with chitosan (CS) and ring-opened polyvinyl pyrrolidone (roPVP) as a swellable mucoadhesive gastroretentive drug dosage form (smGRDDF) were prepared and characterized. CS/roPVP hydrogels were produced by blending CS with roPVP obtained by basic treatment of PVP. Effects of the heating time and NaOH concentration employed for preparing roPVP, and CS molecular weights (Mws), and roPVP/CS ratios on the swelling ability of the resultant hydrogels were characterized....
09. April 2018
This chapter aims to preparation and in-vitro evaluation of ofloxacin floating tablets using different hydrophilic swelling polymers to localize the dosage form in the stomach in order to achieve gastric retention, and hence increase drug stability, sustainment and patient compliance leading to better treatment outcomes
29. February 2016
The purpose of this investigation was to prepare and characterize acyclovir loaded floating microspheres by emulsification solvent evaporation method. Piperine was added to investigate its effect on acyclovir bioavailability. The microspheres were characterized for size, shape, entrapment efficiency, in vitro drug release, and in vivo pharmacokinetic parameters. The morphological characterization of microspheres was done using a scanning electron microscope. The microspheres were spherical and...
18. October 2015
Carboxymethyl starch microspheres (CMS-MS) were produced from carboxymethyl starch powder (CMS-P) with a degree of substitution (DS) from 0.1 to 1.5 in order to investigate the influence of DS on physicochemical, drug release and mucoadhesion properties as well as interactions with gastrointestinal tract (GIT) epithelial barrier models. More
29. April 2015
A multiple-unit floating alginate bead drug delivery system with prolonged stomach retention time was developed in this study. The floating alginate beads were prepared by ionic cross-linking method, using CaCO3 as the gas-forming agent. Over 92% of the beads remained floating after 9 h…. http://www.ncbi.nlm.nih.gov/pubmed/24588740 Drug Dev Ind Pharm. 2015 Apr;41(4):674-80. doi: 10.3109/03639045.2014.893355. Epub 2014 Mar 4.
09. March 2015
Dr. R. Srinivasan1, Sk. Shakir Ahmad1*, D. SK. Sarma1, D. Rajesh Kumar1, Dr. K. Ravi Kumar2, V. Mahesh Swami1 1Siddhartha Institute of Pharmaceutical Sciences, Jonnalagadda, Narsaraopet, Guntur, A.P, India 2Assosciate Professor, Hindu college of Pharmacy, Guntur, Andhra Pradesh, India Received 28 September 2014, Accepted 28 November 2014, Available Online 10 February 2015 Int. J. Med. Pharm. Res., 2015, 3(1): 937-941 http://www.pharmaresearchlibrary.com/wp-content/uploads/2015/02/IJMPR2405.pdf
24. August 2014
presented at ExcipientFest Europe - June 2014 Amsterdam http://www.excipientfest.com/europe/pdf/EFE14%20June%2025,%20A1%20Omyapharm%20introducing%20Functionalized%20Calcium%20Carbonate.pdf