17. April 2018

This article reviews various polysaccharides used in transdermal drug delivery system. The system provides continuous controlled delivery of active ingredients through human skin and into the blood stream. Poor penetration of most drugs into the skin has led to numerous studies being conducted to increase the permeability of such drugs. Currently, the interest to utilize natural polysaccharides in transdermal formulations has increased as an alternative to the synthetic materials. Structure...

10. March 2018

Mucoadhesive tablets for administration in buccal mucosa are unconventional formulations with many technological attractions. However there is no standardization of information for its formulation. The present article aims to evaluate, by means of a systematic review with meta-analysis, the data related to the final quality of this technology.

26. January 2018

The last fifty years, ophthalmic drug delivery research has made much progress, challenging scientists about the advantages and limitations of this drug delivery approach. Topical eye drops are the most commonly used formulation in ocular drug delivery. Despite the good tolerance for patients, this topical administration is only focus on the anterior ocular diseases and had a high precorneal loss of drugs due to the tears production and ocular barriers. Antibiotics are popularly used in solution

18. January 2018

This work addresses the establishment and characterization of gellan gum:pectin (GG:P) biodegradable mucoadhesive beads intended for the colon-targeted delivery of resveratrol (RES). The impact of the polymer carrier system on the cytotoxicity and permeability of RES was evaluated. Beads of circular shape (circularity index of 0.81) with an average diameter of 914 μm, Span index of 0.29, and RES entrapment efficiency of 76% were developed.