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07. August 2017
Formulation of gliclazide in the form of extended- release tablet in 30 and 60 mg dosage forms was performed using hypromellose (HPMC K4M) as a retarding agent. Drug-release profiles were investigated in comparison with references Diamicron MR 30 and 60 mg tablets.
20. June 2016
ABSTRACT Objective: The objective of the work is to formulate gliclazide bioadhesive tablets that will significantly improve the availability of the drug especially under the situations of prolonged use of drug and also reduce the total dosage of administered drug and consequently reduce the side effects. All these factors will ultimately lead to enhanced patient compliance and patient care. Methods: Various natural and semi synthetic polymers were screened and they were selected on the basis...