31. January 2018
Multiple brands of the same active ingredient may be available for the same strength, administration route and dose form. Generic brands needs to demonstrate bioequivalence to the originator brand, but the appearance of the generic and originator brands are not required to match.
31. January 2017
The aim of this study was to apply the knowledge of surface free energy for the flowability prediction of pharmaceutical excipients. In order to predict the flowability, the spreading coefficient was calculated from the surface free energy of each material using Wu's equation. The resulting spreading coefficient could indicate which material would spread over another in a binary mixture. In this study, the binary mixture consisted of filler (lactose, or dibasic calcium phosphate) and a...