14. June 2018
The brand new Glatt TwinPro® is absolutely revolutionary. It combines two previously single batch processes into one single process: High Shear Granulation and Fluidized Bed Drying. Critical aspects like product Transfer and wet sieving are eliminated, process time is enormously shortend. Glatt TwinPro® - Innovation by Experience. TwinPro® is the winner of the Achema 2018 Innovation Award - Category Pharmaceutical Technologies.
11. March 2018
Granulation is an integral step during pharmaceutical manufacturing of solid doses, which is usually followed by unit operations such as drying, milling, tableting and coating. Granulation is typically carried out to alleviate problems in powder handling, content non-uniformity, segregation and poor flow properties of powders. However, previous work carried out by Oka et. al. (Oka, Emady et al. 2015) points out that sometimes a wet granulation process might fail to give us a robust product ..
17. May 2017
•Sugars are soluble and sticky ingredients and their granulation may be difficult.
•Granulation performance of sugars in high shear granulation was evaluated.
•The use of a mixer torque rheometer was used to assess optimal amount of binder.
•The partial solubilization of the sugars increases the viscosity of the liquid bridges.
•
Liquid amount required for the process is function of the sugar thickening power.