05. January 2017

Abstract Microcrystalline cellulose (MCC) is used globally as an inactive ingredient in food and nutraceutical products and is commonly used as a food additive. To confirm the conformity of MCC to the solubility requirements stipulated in international specifications, the solubilities of commercially available MCC products were tested in sodium hydroxide (NaOH) solution. All of the samples were insoluble in NaOH solution, which is inconsistent with the descriptions provided in international...

02. March 2016

Aim: The present work was aimed to formulate Verapamil hydrochloride (HCl) an antihypertensive agent as controlled release (CR) matrix tablets using naturally occurring hydrophobic gum such as dammar gum as a polymer. Methods: In the present investigation, an attempt was made to induce hydrogel formation using polyelectrolytes such as calcium hydroxide and sodium hydroxide with the dammar gum in the presence of dissolution media and to extend the drug release up to 12 h. The hydrogels thus...