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22. May 2017
Nitrendipine amorphous solid dispersions named TDP-PVP and TDP-PEG were prepared.
Hydrogen bond forces were formed between drug and excipient in TDP-PVP and TDP-PEG.
Fit profile of contact angle to get dissolution mechanism of TDP-PVP and TDP-PEG.
TDP-PEG was carrier-controlled and TDP-PVP was drug/carrier-controlled diffusion