19. April 2017

Abstract The objective of this study was to investigate the effect of the different physiological parameters of the gastrointestinal (GI) fluid (pH, buffer capacity, and ionic strength) on the in vitro release of the weakly basic BCS class II drug quetiapine fumarate (QF) from two once-a-day matrix tablet formulations (F1 and F2) developed as potential generic equivalents to Seroquel® XR. F1 tablets were prepared using blends of high and low viscosity grades of hydroxypropyl methylcellulose...

16. November 2016

Context: Sustained release drug delivery systems are more preferred than the conventional drug delivery systems due to its enhanced bioavailability and patient compliance. Earlier studies reported on glibenclamide (GBCM) were not clear and hence, the step has been taken to explore the sustained release drug delivery system of GBCM. Aims: To evaluate the sustained release microspheres obtained of GBCM. Methods: Microspheres were prepared by ionic gelation method using the polymers like Eudragit...

07. December 2015

18. October 2015

12. January 2015

By Dan Stanton+, 12-Jan-2015 Capsugel has acquired a technology platform which uses ionic liquids to enhance the solubility of lipid-based drug delivery systems. http://www.in-pharmatechnologist.com/Drug-Delivery/Capsugel-buys-ionic-liquid-tech-IP-to-up-lipid-based-drug-solubility