28. July 2017
The objective of the current study was to develop an amorphous solid dispersion for a high melting point compound, griseofulvin (GRF), with an enhanced solubility and a controlled release pattern utilizing hot melt extrusion (HME) technology.
27. July 2017
With the XStraw® drinking straw, a product innovation by the company DS-Technology GmbH, the intake of drugs is made incredibly easy and becomes more convenient for patients with swallowing difficulties and the elderly - because drinking with a straw is the most wonderful thing for little ones and grown-ups alike.
27. July 2017
Orally disintegrating tablets (ODTs), also known as orodispersible tablets, are unique dosage forms formulated to improve their in vivo disintegration and dissolution rates. It is a big challenge to ODT producers to achieve a minimum disintegration time while keeping formulation simple and robust.
27. July 2017
Androgenetic alopecia is an extremely common dermatological disorder affecting both men and women. Oral finasteride (FNS), a synthetic 4-aza-3-oxosteroid compound with poor aqueous solubility, blocks the peripheral conversion of testosterone to dihydrotestosterone (DHT) in a significant reduction in DHT concentration, achieving satisfactory results in alopecia treatment.
26. July 2017
Poly(lactide-glycolide) has been used for drug-delivery applications because of its beneficial physicochemical properties, long safety record, and reliable commercial supply.
26. July 2017
Attention on mannitol production by fermentation is received in recent years.
Fermentation factors affected the mannitol yield are listed.
Mannitol applications in food, pharmaceutical and chemical industries are reviewed.
26. July 2017
The aim of this study was to evaluate the suitability of saturated phosphatidylcholine (Phospholipon® 90H) as extended release excipient in matrix tablets for three model drugs with different aqueous solubility (theophylline, caffeine and diprophylline)
26. July 2017
Efficient topical drug delivery systems of norfloxacin have been synthesized.
Norfloxacin loaded to the core of lipid- polymer hybrid nanoparticles were prepared.
The formulations were optimized by factorial design and characterization techniques.
A unique formulation of norfloxacin that offer prolonged and control delivery.
25. July 2017
Therapeutic peptides have become very successful drugs due to their specificity, potency and low toxicity, but they show challenges for their delivery, due to their short half-life and rapid plasma clearance.
25. July 2017
In the present investigation, oral dissolving/dispersible/disintegrating tablets (ODTs) of clopidogrel were designed with a view to enhance the bioavailability and patient compliance by two different methods, namely, direct compression and effervescent methods using directly compressible excipient and treated agar (TAG)