02. July 2015

Phosphate restriction is needed in most dialysis patients. The package inserts from some medications indicate that phosphate may be part of the excipient fraction of drugs. It is unclear whether its amount may be clinically significant since the phosphate content is unquantified. More

01. July 2015

Colorcon officially opened a new technical service laboratory in Beijing, China on June 25, 2015. Located in the Beijing YiZhuang Biomedical Park, this technical centre is in a unique position to work closely with the pharmaceutical research community in the North China region. More

01. July 2015

MUMBAI, India--(BUSINESS WIRE)--IDEAL CURES PVT. LTD. is delighted to announce that it has received third EXCiPACT™ certificate for its manufacturing site located at Vasai. The plant at Vasai is the main manufacturing facility of the company and has received EXCiPACT™ certification for Film Coating Materials (INSTACOAT™, INSTANUTE™, INSTASPRAY™, and INSTAMASK™) and Extended Cooling Boosters (ECOCOOL™). With receipt of this third certificate all manufacturing plants of Ideal Cures...

30. June 2015

In a study published today in the Journal of Pharmaceutical Sciences (link), Professor Strømmes group shows, in collaboration with Associate Professor Christel Bergström's research in pharmacy, that release of pharmaceuticals from Upsalite® can be controlled with great precision by choosing the right size of Upsalite® particles. More

30. June 2015

Amorphous formulations of APIs in polymers tend to absorb water from the atmosphere. This absorption of water can induce API recrystallization, leading to reduced long-term stability during storage. In this work, the phase behavior of different formulations was investigated as a function of relative humidity. Indomethacin and naproxen were chosen as model APIs and poly(vinyl pyrrolidone) (PVP) and poly(vinyl pyrrolidone-co-vinyl acetate) (PVPVA64) as excipients. More

30. June 2015

The development and manufacture of novel nanocarriers for drug delivery has proved challenging with regards to scale-up and pharmaceutical quality. More

29. June 2015

29. June 2015

Molecular dynamics of pure nifedipine and its solid dispersions with modified carbohydrates as well as the crystallization kinetics of API (active pharmaceutical ingredient) above and below the glass transition temperature were studied in detail by means of Broadband Dielectric Spectroscopy (BDS), Differential Scanning Calorimetry (DSC) and X-ray method. More

29. June 2015

Chemists at MIT have created a triple warhead against cancer. They believe theirs is the first example a polymer nanoparticle which carries a precise ratio of three drugs that can be released in response to three distinct triggers. More

28. June 2015

Oxycodone DETERx® is an extended-release (ER), microsphere-in-capsule abuse-deterrent-formulation designed to retain its extended-release properties following tampering or misuse (e.g., chewing, crushing). This study assessed the safety and pharmacokinetics of orally administered intact and crushed Oxycodone DETERx® capsules compared with intact and crushed reformulated OxyContin® tablets and crushed immediate-release oxycodone tablets (IR oxycodone). More