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28. December 2015
The aim of this study was to investigate the effect of combination lipophilic (Acryl-EZE®) and hydrophilic (HPMC) polymers on the release of Sodium Diclofenac (DS) from a tablet. The microgranules were prepared using a fluidized bed followed by direct compression. Swelling and erosion studies of polymer matrix tablets were carried out in various media. More
21. October 2015
Nowadays exploration of novel lipid-based formulations is akin to a magnet for researchers worldwide for improving the in vivo performance of highly lipophilic drugs. Over the last few years, new compositions of lipids have been developed, and the probable bioavailability enhancement has been investigated. We reviewed the most recent data dealing with backlogs of conventional lipid-based formulations such as physical instability, limited drug loading capacities, drug expulsion during storage...