16. February 2018
A common obstacle encountered in the early stages of drug development is the formulation of poorly water-soluble drugs (PWSDs). One effective approach to improve the dissolution of PWSDs is to render such drugs into their amorphous or disordered form.
16. January 2018
Nowadays, the pharmaceutical industry is facing an increasing numbers of low solubility drug candidates and this issue o en hinders those compounds from achieving su cient oral bioavailability. In order to alleviate this challenge, many enabling formulation technologies have been developed. Of these, liquid- lled capsules have emerged as one of the key technologies for oral drug delivery of low solubility compounds.
07. August 2017
Many drug candidates today have a low aqueous solubility, and hence may show a low oral bioavailability, presenting a major formulation and drug delivery challenge. One way to increase the bioavailability of these drugs is to use a supersaturating drug delivery strategy.