13. August 2018
3D printing is an additive manufacturing technique capable of producing various 3D drug products, medical devices, tissues and organs from digital designs. The first FDA approved 3D drug product, Spritam®, has encouraged and attracted many researchers in this field with research undergoing to develop various customized dosage forms. This review aims to introduce 3D printing, its history, advantages, challenges and various techniques used in fabrication of drug products. This review also...
11. December 2017
Use of a self-microemulsifying drug delivery system (SMEDDS) is widely known as one of the most effective approaches to overcome problems associated with low solubility and poor oral absorption of water-insoluble drugs. Previously, we have demonstrated that a super saturable SMEDDS (SuSMEDDS) greatly contributed to enhanced dissolution and oral absorption of valsartan (VST), a drug with poor solubility in water ...
11. July 2017
The taste of pharmaceuticals strongly affects the compliance of patients. This study investigated the applicability of the electronic tongue and rodent brief-access taste aversion (BATA) model for the bitter compound praziquantel (PZQ) and taste masked liquid formulations for PZQ.
17. June 2016
Abstract Three granulation processing methods; Hot melt extrusion (HME), Roller compaction Dry granulation (RCDG) and Moisture assisted dry granulation (MADG) are assessed to evaluate different polymeric binders for preparation of a high dose immediate release tablet of acetaminophen drug. Different characterization techniques were used to enumerate poor physical property characteristic for drug (paracetamol) including hygroscopicity, low solubility and bulk density, and poor powder...
19. August 2015
Prostate cancer (PCa) disease progression is associated with significant changes in intracellular and extracellular proteins, intracellular signaling mechanism, and cancer cell phenotype. These changes may have direct impact on the cellular interactions with nanocarriers; hence, there is the need for a much-detailed understanding, as nanocarrier cellular internalization and intracellular sorting mechanism correlate directly with bioavailability and clinical efficacy. More
06. April 2015
Int J Pharm Investig. 2015 Apr-Jun; 5(2): 101–106. doi: 10.4103/2230-973X.153387 Suryadevara Vidyadhara, Reddyvallam Lankapalli Sasidhar, Thalamanchi Balakrishna, and Malapolu Santha Vardhan Department of Pharmaceutics, Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Chowdavaram, Guntur, Andhra Pradesh, India Address for correspondence: Dr. S. Vidyadhara, Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Chowdavaram, Chandramoulipuram, Guntur - 522 019, Andhra Pradesh, India....