30. March 2015

Elsevier - Powder Technology - Available online 21 March 2015 This work focuses on the content non-homogeneity in granules across size classes in a high shear wet granulation process as a result of powder segregation during dry mixing coupled with preferential wettability of the one of the ingredients with the binder fluid... http://www.sciencedirect.com/science/article/pii/S0032591015002132

30. March 2015

Received 5 December 2014, Revised 24 March 2015, Accepted 25 March 2015, Available online 27 March 2015 http://www.sciencedirect.com/science/article/pii/S0168365915002084

30. March 2015

Abstract: This study describes the preparation, characterization and performance of a novel excipient for use in oro-dispersible tablets (ODT). The excipient (Cop–CM) consists of chitin and mannitol. The excipient with optimal physicochemical properties was obtained at a chitin: mannitol ratio of 2:8 (w/w) and produced by roll compaction (RC). Differential scanning calorimetry (DSC), Fourier transform-Infrared (FT-IR), X-ray powder diffraction (XRPD) and scanning electron microscope (SEM)...

27. March 2015

Pharm Dev Technol. 2015 Mar 23:1-8. [Epub ahead of print] Comoglu T1, Inal O, Yaacoub HB. rugs exhibiting satisfactory absorption from the oral mucosa or intended for immediate pharmacological action can be advantageously formulated as orally fast-disintegrating tablets (FDTs or ODTs). .. http://www.ncbi.nlm.nih.gov/pubmed/25798913

27. March 2015

J Drug Deliv. 2015; 2015: 640529. Published online 2015 Feb 25. doi: 10.1155/2015/640529 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355560/?tool=pmcentrez

27. March 2015

By Gareth MacDonald+, 26-Mar-2015 Capsugel will invest $25m (€22m) to expand production of vegetarian-friendly drug and food supplement capsules. http://www.in-pharmatechnologist.com/Drug-Delivery/Capsugel-invests-25m-in-vegetarian-drug-capsules

26. March 2015

By Staff ReporterStaff Reporter, 25-Mar-2015Want the latest market information, and scientific insights in the pharmaceutical excipients market? Then join us at our free online event, Excipients Innovations 2015.http://www.in-pharmatechnologist.com/Product-Categories/Excipients-raw-materials-and-intermediates/The-latest-developments-in-drug-excipients-Exclusive-online-event

25. March 2015

By Fiona Barry +Fiona BARRY, 25-Mar-2015The European Commission has published guidelines on GMP excipients after a two-year consultation. http://www.in-pharmatechnologist.com/Processing/GMP-for-excipients-new-EU-rules-on-raw-materials-packaging-tracking

25. March 2015

Kwabena Ofori-Kwakye, Kwadwo Amanor Mfoafo, Samuel Lugrie Kipo, Noble Kuntworbe, Mariam El Boakye-Gyasi Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana Received 13 February 2015, Accepted 13 March 2015, Available online 20 March 2015Open Access funded by King Saud University http://www.sciencedirect.com/science/article/pii/S1319016415000687

24. March 2015

The solid dispersion has become an established solubilization technology for poorly water soluble drugs. Since a solid dispersion is basically a drug–polymer two-component system, the drug–polymer interaction is the determining factor in its design and performance. In this review, we summarize our current understanding of solid dispersions both in the solid state and in dissolution, emphasizing the fundamental aspects of this important Technology....