31. May 2017

EXCiPACT asbl is delighted to announce that the Ashland Speciality Ingredients site in Doel, Belgium has recently been awarded an EXCiPACT GMP Certificate from SGS, one of EXCIPACT’s internationally-recognised Certification Bodies. The Certificate demonstrates that the Ashland Speciality Ingredients (ASI) site in Doel, Belgium, manufactures pharmaceutical excipients according to the EXCiPACT Good Manufacturing Practice (GMP) Certification Standard. Its scope covers the production of...

31. May 2017

Praziquantel, a BCS II class anthelmintic drug used for the treatment of schistosome infections, was coground in a vibrational mill with different polymers (linear and crosslinked povidone, copovidone and sodium starch glycolate

31. May 2017

In a nanotechnological approach we have investigated the use of natural lipids in the preparation of nanostructured lipid carriers (NLC).

31. May 2017

Diabetes mellitus is one of the most grave and lethal non communicable diseases. Insulin is normally used to medicate diabetes. Due to bioavailability issues, the most regular route of administration is through injection, which may pose compliance problems to treatment. The oral administration thus appears as a suitable alternative, but with several important problems

31. May 2017

Piracetam was investigated as a model API which is known to exhibit a number of different polymorphic forms. It is freely soluble in water so the possibility exists for polymorphic transformations to occur during wet granulation

29. May 2017

We previously determined “Tableting properties” by using a multi-functional single-punch tablet press (GTP-1). We proposed plotting “Compactability” on the x-axis against “Manufacturability” on the y-axis to allow visual evaluation of “Tableting properties”.

29. May 2017

In the manufacturing industry, equipment precision and instrument accuracy play a large role in the overall turnover of the organization. This is because the performance of the machinery and its accuracy in terms of output can significantly alter the quality of the goods being produced.

29. May 2017

Self-emulsifying drug delivery systems (SEDDS) are lipid formulations that improve solubility and oral bioavailability of the incorporated drug with poor biopharmaceutical properties. As liquids they are traditionally filled into soft or hard capsules.

29. May 2017

The present investigation was carried out to understand the impact of formulation and process variables on the quality of oral disintegrating films (ODF) using Quality by Design (QbD) approach.