27. February 2018
Novel medicated straws were developed based on drug-loaded
electrospun fibers prepared by direct current electrospinning
(DCES) and high-speed electrospinning (HSES) of scaled-up
productivity. Good quality micro- and nanofibers were
electrospun using both techniques despite the multiple times
higher throughput rate of HSES based on the scanning electron
microscopic imaging (SEM). Solid state analyses revealed that
the poorly soluble model drug carvedilol (CAR) was dispersed
in an amorphous form