26. June 2018
More and more pharmaceutical products are reaching the market as multiparticulate dosage forms, mainly as pellets. The healthcare sector also frequently selects pellets as the optimal marketable form of functional food. As there are quite a number of existing techniques relating to the production of pellets, it is often very difficult for a formulator or marketing manager to make a choice, since every technique claims to be optimal.
12. November 2017
Taste masking increases drug acceptability and medication adherence in pediatric, geriatric, and other special patient populations.
02. October 2017
Experienced CDMO partner for solid dosage forms - Innovative solutions for multiparticulates, pellets and micro pellets
Pediatric formulation - Quality by Design and Scale up concepts - Clinical trial and commercial bulk manufacturing - Controlled substances / organic solvents handling- GMP / FDA sites in Binzen/Germany and Ramsey/USA
02. May 2017
The multiparticulate drug product concept covering micropellets, pellets and mini-tablets is presented as a highly feasible approach to present convenient and patient friendly medication for the geriatric population. Improved swallowability and optimized administration regimen going along with defined drug dosage are
achievable. Extemporaneous preparation of medicines from standard medication can
be avoided going along with improved patient safety.
03. April 2017
ABSTRACT The aim of the present work was to develop and evaluate sustained release colon targeted micropellets of lornoxicam in order to achieve release of the drug at colon which could result in enhanced local absorption and thereby improved bio-availability. The present worker prepared micropellets of lornoxicam in nine batches using pure drug, DCP, PVPK-30 and different ratios of HPMCK-4M taking into account the direct pelletization technique. Resulted micropellets were illed in capsules and...
26. October 2016
Abstract The multiparticulate drug product concept covering micropellets, pellets, and mini-tablets is presented as a highly feasible approach to present convenient and patient friendly medication for the geriatric population. Improved swallowability and optimized administration regimen going along with defined drug dosage are achievable. Extemporaneous preparation of medicines from standard medication can be avoided going along with improved patient safety. With one multiparticulate pellet,...
01. February 2016
We aimed to develop a suitable micropellet delivery system for Lansoprazole, a highly potent proton pump inhibitor and acid-unstable physiologically active anti-secretory compound. Although clinically manifested to be highly effective for treating acid reux-related diseases, poor water solubility and short gastric retention time, typically does not provide extended period of relief. Materials and method: Micropellets of the drug was prepared using ionotropic gelation technique, where gelation...
13. January 2016
Individual dosing of medicines is relevant for paediatrics, geriatrics and personalised medicine. The Solid Dosage Pen (SDP) allows for individual dosing by cutting monolithic, tablet-like drug carriers of pre-defined heights. The aim of the present study was to develop micropellet-loaded rods (MPLRs) with dose-independent sustained release properties for individual dosing via the Solid Dosage Pen. More
23. October 2015
TTC Technology Training Center Workshop 24 - 26 November 2015 in Binzen, Germany This workshop aims to elaborate the advantages and drawbacks of the individual techniques, focusing on the optimal spectrum of each one but also consider the economical and ergonomical aspects of manufacturing processes More Information & Registration