02. January 2018
Natural mucilage’s are included in novel drug delivered (NDDS) to multitask functions and in any cases directly or indirectly control the increase and rate of drug release. Substantial research efforts have been directed towards develop safe and efficient natural based mucilage particulate drug delivery systems., natural gums and mucilages and their isolation, purification, standardization and characterization characteristics along with their applications are covered.
09. February 2017
ABSTRACT Objective: Transmucosal buccal drug delivery could be an alternative for oral administration for systemic delivery of Verapamil Hydrochloride (VH), as it has low bioavailability 20 - 35 % due to its extensive rst pass metabo- lism and variable absorption at GIT. Method: Buccal patches of VH were prepared by solvent casting method using bioadhesive polymers HPMC K4M, Carbopol 934P, Chitosan acetate and Okra mucilage isolated from Hibiscus esculantus fruits, in various combinations as...
07. April 2016
Aim: To develop and evaluate interpolymer complex based buccal mucoadhesive films of Tramadol Hydrochloride. The interpolymer complex was prepared by using Chitosan and Aloe vera gel mucilage. Materials and Methods: In present study the inter polymer complex is formed between mucoadhesive polymer chitosan and aloe vera gel mucilage. The resulted interpolymer complex is used to prepare buccal mucoadhesive films of Tramadol Hydrochloride, an opioid analgesic. Other excipients includes glycerin as...