14. December 2016
Abstract The purpose of the study was to develop and evaluate a tripartite novel excipient for direct compression of salbutamol tablets. Various batches (A-E) of the novel excipient was prepared by co-processing varying concentrations of okro gum with gelatinized maize starch and lactose using co-precipitation method. The novel excipient powders were subjected to some physicochemical evaluations. Batches (F-H) of the physical mixture of the novel excipient ingredients were also prepared. The...
09. March 2016
In this study a gastric-retentive delivery system was prepared by a novel method which is reported here for the first time. An innovative floating and bioadhesive drug delivery system with a hollow structure was designed and prepared. The floating and bioadhesive drug delivery system was composed of a hollow spherical shell, a waterproof layer (Stearic acid), a drug layer (Ofloxacin), a release retarding film (the novel blended coating materials) and a bioadhesive layer (Carbomer 934P) prepared...
20. February 2016
Aim: The aim was to develop a novel excipient from Pleurotus tuber-regium (PT)-cornstarch (CS) mixture and evaluate its multifunctional characteristics in tablet formulation. Materials and Methods: Composites were generated from dephytochemicalized PT and CS combined at 1:1 to 4:1 ratios and pregelatinized in a hot water bath at 65°C ± 2°C for 5 min. The paste was dried, pulverized, and screened through 150-μm sieve. PT-CS physical mixtures were prepared and their characteristics /...
07. November 2015
FELICITAS GUTH*, HEIKO A. SCHIFFTER, KARL KOLTER *Corresponding author BASF SE, Formulation Nutrition & Health, Carl Bosch Str. 38, 67056 Ludwigshafen, Germany More
04. November 2015
The authors present an update to the Wyeth/BASF experience with the IPEC Novel Excipient Safety Evaluation Procedure. Nov 02, 2010 By Ranga Velagaleti, PhD [1], Sherry Ku [2] Pharmaceutical Technology
22. July 2015
By Zachary Brennan+, 22-Jul-2015 As part of a push to bring more novel excipients to market, IPEC-Americas is calling on the FDA to create a new regulatory review process that could relieve some of the uncertainty around the use of new excipients. More
24. April 2015
Released by Jungbunzlauer April 23, 2015 TCC TB is a tricalcium citrate tetrahydrate designed to function as a direct compression excipient. See more at: http://www.nutraceuticalsworld.com/contents/view_white-papers-tech-papers/2015-04-23/tcc-tb---novel-excipient-for-direct-compression/#sthash.ZF8655ye.dpuf