10. June 2018
The focus of the OSeeT are enteric coatings (EC) and modified-release (MR) coatings. The characteristics of the coating layer are revealed via OSeeT: Mean coating thickness → progress of coating process Intra-particle and inter-particle coating variability → for quality and homogeneity of the applied coating Roughness → optical quality of the surface The Technology behind OSeeT is Interferometry OCT is based on white light interferometry: – broad bandwidth resulting in low-coherence...
15. December 2016
Abstract There is ample evidence that pharmaceutical excipients, which are supposed to be pharmacologically inactive, have an impact on drug metabolism and efflux transport. So far, little is known whether they also modulate uptake transporter proteins. We have recently shown that commonly used solubilizing agents exert significant effects on the function of organic anion uptake transporting polypeptides. Therefore, we investigated in this study the influence of frequently used pharmaceutical...