06. July 2015

Highlights •Synthesis and characterization of cysteamine conjugated β-cyclodextrin (β-CD-Cys). •Conjugates showed no toxic effects on Caco-2 cells at concentrations of 0.5% (m/v). •Maximum 34.51-fold improved mucoadhesion on the porcine buccal mucosa. •Inclusion complexes resulted in 150-fold increased water solubility of miconazole nitrate. More