06. February 2018
Oral Disintegrating Tablets (ODTs) is a novel dosage form that can be dissolved on the tongue within 3min or less especially for geriatric and pediatric patients. Current ODT formulation studies usually rely on the personal experience of pharmaceutical experts and trial-and-error in the laboratory, which is inefficient and time-consuming. The aim of current research was to establish the prediction model of ODT formulations with direct compression process by Artificial Neural Network (ANN) and...
25. November 2017
In this study, within the framework of Quality by Design which is a systemati- cally scientific approach which enables to understand and control the production and formulation variables during the process design and development, different parameters in the formulation and production process were detected and criti- cal process parameters and critical material attributes were determined via risk evaluation methods. Then, different oral disintegrating tablet formulations were prepared and tested b
26. June 2017
Most of the drug products available in the market are for oral drug administration. Oral route is preferred due to ease of administration, versatility, patient compliance and accurate dosing. However, oral administration is not suitable for people with dysphasia, a condition that results in difficulty in swallowing.