04. June 2018
The selection of the excipient(s) for a tablet formulation should take into account the API properties, process, target formulation and potential impact on the formulation. Some of those API properties can be Dose Particle Size Flow Properties Bulk Density Moisture Content Hygroscopicity Excipient Compatibility Compactability The following tables show some possible impacts on the tablet formulation and considerations to take into account. Pharmaexcipients.com thanks Fred Monsuur, Grace for the...
26. April 2018
Are you a manufacturer of raw materials for the food, nutraceutical or pharmaceutical industry and interested to increase your product performance or functionality? Are topics like Dust free Solubility Protection Taste masking Targeted release Particle size Flowability relevant to you or for the life cycle management of your product? Then come to speak with the experts from IPC Process Center @Vitafoods Geneva Stand T167 - May 15-17, 2018. If not attending just drop us an email. Further...
12. October 2017
Poor aqueous solubility leading to poor oral bioavailability is a bottle neck in the development of many new drug candidates; particularly the BCS class II-IV drugs. These molecules are difficult to formulate using conventional approaches and are associated with numerous formulation related performance issues.
29. September 2017
The aim of this study was to investigate hydrophilic-hydrophobic conjugates as new carriers for nano-sized solid dispersions (SDs).
15. August 2017
Powder blend homogeneity is a critical attribute in formulation development of low dose and potent active pharmaceutical ingredients (API) yet a complex process with multiple contrib- uting factors.
21. June 2017
Powder blend homogeneity is a critical attribute in formulation development of low dose and potent active pharmaceutical ingredients (API) yet a complex process with multiple contributing factors. Excipient characteristics play key role in efficient blending process and final product quality. In this work the effect of excipient type and properties, blending technique and processing time on content uniformity was investigated.
16. June 2017
Powder blend homogeneity is a critical attribute in formulation development of low dose and potent active pharmaceutical ingredients (API) yet a complex process with multiple contributing factors. Excipient characteristics play key role in efficient blending process and final product quality.