20. July 2018
Solid dispersions are an effective formulation technique to improve the solubility, dissolution rate, and bioavailability of water-insoluble drugs for oral delivery. In the last 15 years, increased attention was focused on this technology. There were 23 marketed drugs prepared by solid dispersion techniques. Objective: This study aimed to report the big picture of solid dispersion research from 1980 to 2015. Method: Scientific knowledge mapping tools were used for the qualitative and the...
19. January 2016
As pharma deals with patent cliffs, reduced healthcare spending and increasingly stringent regulations, drug development has become more challenging. New excipients could offer much-needed opportunities, but how can you make the right choice? Dr Rajsekhar Paul, senior scientist at Novartis, shares his views. More
11. August 2015
A process for producing a composition which is particularly rich in D-mannitol, the latter being present in the form of crystals having a volume average diameter greater than 20 μm, wherein the crystals correspond to a very large extent to the δ polymorph. This process makes use of the evaporative crystallization technique, in which the seeding and then the controlled growth of the crystals is carried out at different evaporation rates. Finally, very pure δ crystals are advantageously...
20. February 2015
http://www.4-traders.com/ASAHI-KASEI-CORP-6491172/news/Asahi-Kasei--Patent-Issued-for-Composite-Particles-Which-Contain-Both-Cellulose-and-Inorganic-Compo-19899277/