25. September 2017
Photodegradation is one of the major pathways of the degradation of drugs. Some therapeutic agents and excipients are highly sensitive to light and undergo significant degradation, challenging the quality and the stability of the final product.
30. June 2017
The purpose of this study is to evaluate the photostabilization mechanism of risperidone tablets. Risperidone is
widely used for sensory integration disorder. It is formulated as tablets, orally disintegrating tablets, fine granules,
oral solutions, and intramuscular injections.
02. August 2016
Abstract Lumichrome (Lc) is a photodegradation product of riboflavin that can be used as a photosensitizer (PS) in antibacterial photodynamic therapy (aPDT). The binding of Lc with plasma proteins such as human serum albumin (HSA) could affect its efficiency as PS. Excipients are necessary to prepare stable formulations to be used in aPDT and they may affect the PS-HSA binding. Hydroxypropyl (HP)-α, β, γ-cyclodextrin (CD), polyethylene glycol 400 (PEG400) and Pluronic® F-127 (PF127) were...