07. April 2017

Abstract Phthalates are known endocrine disruptors. Not commonly recognised, phthalates are used as excipients in a number of drug formulations. We aimed to describe the sale of phthalate-containing drugs in Denmark from 2004 to 2015. National data on annual sale of medications (tablets only) were accessed from medstat.dk. Data from the Danish Medicines Agency on phthalate content per tablet were merged with data on total sale for each active substance and drug formulation. We used the...

25. June 2016

Abstract In this study we present the use of co-axial electrospinning to produce core-shell composite micro-/nano- fibers of Polyurethane (PU) and Cellulose acetate phthalate (CAP). The designed fibers possess enhanced mechanical properties with a tensile strength of 13.27 ± 2.32 MPa, which is a clear improvement over the existing CAP fibers that suffer from a poor mechanical strength (0.2 ± 0.03 MPa). The CAP imparts pH responsiveness to the core-shell structure giving the fibers potential...

11. April 2015

25. November 2014

By Zachary Brennan+, 25-Nov-2014 The two guidelines offer help to manufacturers looking to use potentially hazardous phthalates as excipients in drugs, as well as those that have shared facilities where multiple drugs are produced. http://www.in-pharmatechnologist.com/Regulatory-Safety/EMA-adopts-guidelines-on-phthalate-excipients-cross-contamination