02. April 2017

Abstract Artemisinin, a natural anti-malarial agent, also possesses anti-proliferative and anti-angiogenic activity in cancer cells with very low toxicity to normal healthy cells. Drug loaded magnetic nanoparticlesby using external magnetic field could selectively accumulate the drug at the target site and thereby reduce the doses required to achieve therapeutic concentration which may otherwise produce serious side effects on healthy cells. In the present study the artemisinin magnetic...

17. July 2016

Abstract Aim: To prepare BSA loaded chitosan nanoparticles by polymerization technique and to study the effect of initiator concentration upon particle size, product yield, entrapment efficiency, loading capacity and drug release from the formulation. Methodology: In the present study BSA loaded chitosan nanoparticles were prepared by polymerization technique. Three formulations were prepared by varying the concentration of Initiator. The concentration of Initiator (Ammonium per sulphate) was...

24. June 2016

Abstract The aim of this study was the development of zeta potential changing self-emulsifying drug delivery systems (SEDDS). Various cationic surfactants were incorporated into a formulation consisting of 30% Cremophor EL, 30% Capmul MCM, 30% Captex 355 and 10% propylene glycol (w/w). A substrate of intestinal alkaline phosphatase (IAP), 1,2-dipalmitoyl-sn-glycero-3-phosphatidic acid sodium (PA), was thereafter incorporated into SEDDS. Size, zeta potential and polydispersity index were...

25. June 2015

This study was initiated with the intention to deliver low aqueous soluble ketoprofen to enhance its solubility by developing microemulsion system as a template and then incorporating it into gel Phase. More