28. December 2016

Aim: The main objective of the present investigation was to formulate and characterize an oral pulsatile drug delivery system of flurbiprofen, for time dependent release, based on chronomodulated approach for the management of rheumatoid arthritis. Settings and Design: The drug delivery system was designed to deliver the drug with a lag time to release the drug when it could be most needful to patients of rheumatoid arthritis. Materials and Methods: Rapid release core tablets of flurbiprofen...