02. May 2018

An increase in the proportion of poorly aqueous soluble drugs that exhibit problems in oral bioavailability is one of the major problems in formulation development. Formulation of lipid-based nanocarriers, such as self-nanoemulsifying drug delivery systems (SNEDDS) and self-microemulsifying drug delivery systems (SMEDDS) have received a lot of attention in recent years as an approach for overcoming poor solubility and oral bioavailability of drugs. SNEDDS are isotropic mixtures of oil,...