15. December 2017
Formulators usually face three kinds of challenges while addressing sensory quality. Firstly, when existing products are changed, the sensory properties should feel the same for customers and patients. In addition to that, sensory problems like formulations that are too greasy, sticky or contain other negative feelings must be tackled. Lastly, you should send positive and beneficial sensory messages to the patients while designing the formulation.
11. August 2016
Many pediatric patients require medications that are not available in age appropriate formulations, especially those with cardiovascular diseases. The use of a suitable vehicle is critical for the preparation of extemporaneous formulations with the expected effect. Considering that palatability is essential to treatment adherence in children, we analyzed the acceptance of extemporaneous formulations of Captopril and Furosemide prepared using a developed vehicle in three flavors: neutral,...
28. July 2016
Abstract Multiparticulate formulations are composed of multiple solid dosage units which can be administered directly to the mouth or sprinkled on food. Oral grittiness (i.e. rough mouthfeel) may arise from the presence of particles in the mouth, limiting palatability. In this work, multiparticulate formulations were prepared by dispersion of spherical granules into orange flavoured vehicles thickened with hypromellose (HPMC) at different viscosities in order to assess oral perception of...