25. May 2016

Abstract: The main aim of the present work was to develop colon specific piroxicam loaded alginate microspheres intended for the treatment of rheumatoid arthritis. A multiparticulate system with a combined property of pH sensitive and biodegradability was developed. Piroxicam microspheres were prepared by using ionotropic gelation technique and coated by using coacervation phase separation method using different ratios of eudragit S100 which is a pH sensitive polymer. Both coated and uncoated...

26. February 2016

Excipients are essential for solubility enhancing formulations. Hence it is important to understand how additives impact key solution properties, particularly when supersaturated solutions are generated by dissolution of the solubility enhancing formulation. Herein, the impact of different concentrations of dissolved polymers on the thermodynamic and kinetic properties of supersaturated solutions of danazol were investigated. More

17. April 2015

Jerry L. Atwood Cryst. Growth Des., Just Accepted Manuscript DOI: 10.1021/acs.cgd.5b00317 Publication Date (Web): April 16, 2015 Copyright © 2015 American Chemical Society http://pubs.acs.org/doi/abs/10.1021/acs.cgd.5b00317?journalCode=cgdefu