19. September 2017
Fluid bed coating offers potential advantages as a formulation platform for amorphous solid dispersions (ASDs) of poorly soluble drugs, being a one-step manufacturing process which could reduce therisk of phase separation associated with multiple step manufacturing approaches. However, the impact of the physicochemical nature of carrier spheres on the properties and drug release from the ASDshas not been studied in detail. In this work, tartaric acid (TAP) and microcrystalline cellulose (CEL)...
01. June 2017
Oral route remains the gold standard for drug delivery despite the new trends in the development of complex biotech therapeutic agents under specialty or biologic categories. This is mainly due to the patient preference for solid dosage forms, convenience of administration, accuracy of dosing, and therefore safety of the patients.