07. September 2018

Lipid excipients for topical drug delivery include solubilizers, emulsifiers and viscosity modifying agents. Emulsifiers are designed for challenging formulations and deliver excellent texture and sensorial properties. Solubilizers provide skin penetration enhancement and viscosity agents stabilize formulations

01. November 2017

Emulgels have been extensively employed as emerging drug delivery systems for the administration of lipophilic or hydrophobic drugs, particularly as a boon for dermal health and cosmetic science. Emulgels are considered as emulsions of either oil–in-water (O/W) or water-in-oil (W/O) type in which the gels are incorporated.

13. August 2017

During the development of a dermal drug, much efforts tend to be placed on improving its delivery through skin. These efforts are driven by the known risk of not engaging the target. Indeed to increase comfort that the target will be engaged one need to try fullfill as best as it can evidence of (1) sufficient compound on board for a desired time (i.e., PK within skin) and (2) demonstration of pharmacological activity [1].

11. July 2017

Skin is considered as an important route of administration of drugs for both local and systemic effect. The effectiveness of topical therapy depends on the physicochemical properties of the drug and adherence of the patient to the treatment regimen as well as the system's ability to adhere to skin during the therapy so as to promote drug penetration through the skin barrier.