30. January 2017

Abstract: This work is the continuation of a study focused on establishing relations between surface thermodynamic properties and in vitro release mechanisms using a model drug (ampicillin trihydrate), besides analyzing the granulometric properties of new polymeric materials and thus establishing the potential to be used in the pharmaceutical field as modified delivery excipients. To do this, we used copolymeric materials derived from maleic anhydride with decreasing polarity corresponding to...

10. March 2016

ABSTRACT Six batches of formulated sustained release matrix tablets of Cefixime Trihydrate were prepared by using different polymers like Tamarind Gum, Carnauba wax, HPMC, MCC, PVP K30 by wet granulation technique. The effects of prepared tablets by using natural polymers were evaluated for pre compression parameters, uniformity of content, assay and in vitro drug release. Influences of different parameters like pH, agitation intensity on drug release were also studied. Cefixime Trihydrate...