18. April 2016

The biopharmaceutical studies have undoubtedly proven that pharmacopoeial excipients based on polyethylene oxide, sodium carboxymethyl cellulose and apple pectin can release pharmacologically active substances and produce pharmacopoeial excipients in the form of ointments and pastes. The dynamics of diffusion of biologically active substances in agar gel within 6 hours of the experiment was practically the same in all samples. The least significant changes in samples consistency and...

09. February 2016

The purpose of this study was to investigate the influence of different hydrophilic polymers on the swelling, bioadhesion and mechanical strength of hydrocolloid wound dressings (HCDs) in order to provide an appropriate composition for a hydrocolloid wound dressing system. In this study, the HCDs were prepared with styrene-isoprene-styrene copolymer (SIS) and polyisobutylene (PIB) as the base using a hot melting method. Additionally, numerous SIS/PIB-based HCDs were prepared with six...

21. June 2015

Abstract Effective assessment and management of wound pain can facilitate both improvements in healing rates and overall quality of life. From a pharmacological perspective, topical application of nonsteroidal anti-inflammatory drugs in the form of film wound dressings may be a good choice. Thus, the aim of this work was to develop novel layered film wound dressings containing ibuprofen based on partially substituted fibrous sodium carboxymethylcellulose (nonwoven textile Hcel NaT). To this...