Safety of Excipients in Pediatric Formulations—A Call for Toxicity Studies in Juvenile Animals?

The development of drug products for pediatric use often requires age-appropriate formulations which can be more complex and may involve a broader range of excipients than adult dosage forms. Excipients established for adult use are not always appropriate for use in children because they can affect children differently than adults....

 

Georg Schmitt

F. Hoffmann-La Roche Ltd., Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel CH-4070, Switzerland; E-Mail: georg.schmitt@roche.com; Tel.: +41-61-688-7576; Fax: +41-61-688-8101

Academic Editors: Johannes N. van den Anker and Klaus Rose 

 

Children 2015, 2, 191-197; doi:10.3390/children2020191

 

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