Contamination of powders and granules by foreign particles - Mechanical detection and extraction

In the production process of a pharmaceutical dosage form there are many sources of foreign particles to be included in the product starting at the production of API and excipients right up to the preparation and production on the final drug product. Contamination sources can be many including human interaction, equipment, process, etc.

 

The current way to detect such particles is by visual inspection by human with several drawbacks such as:

  • Light 
  • Repetitive accuracy
  • Accuracy of Detection relative to size and contrast
  • Validation of the process 
  • Throughput and cost factor

There are solutions to detect and extract such foreign particles mechanically with a high precision from powders and granules before they end in the final product.

 

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