Understanding Drug-Excipient Interactions - Presentation A. Carlin - ExcipientFest 2009

Excipients are more complex than well-characterized active pharmaceutical ingredients (“APIs”). Often, it is the multi-component nature of the excipient that drives many of the interactions with APIs. Even for the most commonly used excipients, it is necessary to understand the context of their manufacture in order to identify potential API interactions with trace components. This workshop will illustrate the contrasting nature of excipients, and help identify reaction mechanisms. This session is recommended for industry professionals in manufacturing, formulation, quality, and technical service functions dealing with drug degradations.