30. July 2018
Three-dimensional printing is one of the fastest developing technology withinpharmaceutical field. With many advantages this method can be found as a new dosageform manufacturing technique, however low printing efficiency stays as one of the major limitations. Therefore, the preparation of filaments as a feedstock and printing of the final dosageforms in pharmacies may by the direction of development for this method. Thus, simple dosage and dissolution profile modification seems to be...
18. April 2017
Abstract The structural changes of crystalline atorvastatin upon high-energy ball milling at room temperature have been studied. The study investigates the effect of polyvinylpyrrolidone (PVP) and hydroxypropylmethyl cellulose (HPMC) polymeric matrix on stabilizing amorphous atorvastatin before and after storage under ambient and elevated humidity conditions. The materials were characterized by X-ray diffraction (XRD), Fourier transform infrared spectrophotometry (FTIR), differential scanning...