25. August 2018
In recent years, excipient development has become a core area of research in pharmaceutical drug delivery because it influences the formulation development and drug delivery process in various ways. Polymeric drug delivery systems have been of great interest for controlled delivery as they show the great advantage in drug delivery systems because of optimized drug loading and releasing property. Then, the side effects of synthetic polymers far exceed that it leads to some difficulties like they...
15. January 2018
In line with the increasing demand for sustainable packaging materials, this contribution aimed to investigate the film-forming properties of hydroxypropyl methylcellulose (HPMC) to correlate its chemical structure with film properties. The roles played by substitution degree (SD) and molecular weight (Mw) on the mechanical and water barrier properties of HPMC films were elucidated.
22. May 2017
Nowadays, biopolymers, a class of biomaterials, represent frontier area in the drug delivery systems. Drug release from nano- and microparticles is a complex process, which involves several steps. Uptake of nanoparticle in the intracellular is affected by numerous factors. Recently, gene delivery has been considered one of the promising approaches for the treatment of various diseases acquired genetically in human being.
05. November 2016
The major challenge in pharmaceutical research is the improvement of drug efficacy, including enhancement of solubility and permeability, leading to an improved oral bioavailability of drugs. Semi-Synthetic Biopolymer Complexes (SSBC) as drug nano-enabled delivery systems have gained significant interest in recent years. Their significance originated from the fact that they show great potential as drug nano-carriers used for oral drug delivery. This resulted from their exceptional properties...
16. February 2015
Denise F. S. Petri* Article first published online: 16 FEB 2015 DOI: 10.1002/app.42035 http://onlinelibrary.wiley.com/doi/10.1002/app.42035/abstract