THE APPLICATION OF SEMI-SYNTHETIC BIOPOLYMER NANO-CARRIER COMPLEXES FOR DRUGS WITH LOW ORAL BIOAVAILABILITY

The major challenge in pharmaceutical research is the improvement of drug efficacy, including enhancement of solubility and permeability, leading to an improved oral bioavailability of drugs. Semi-Synthetic Biopolymer Complexes (SSBC) as drug nano-enabled delivery systems have gained significant interest in recent years. Their significance originated from the fact that they show great potential as drug nano-carriers used for oral drug delivery. This resulted from their exceptional properties obtained by merging the properties of synthetic (e.g. good thermal and mechanical properties) with natural polymers (e.g. biocompatibility); thus forming a new class of biopolymeric materials combining the best of both aspects.

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THE APPLICATION OF SEMI-SYNTHETIC BIOPOLYMER NANO-CARRIER COMPLEXES FOR DRUGS WITH LOW ORAL BIOAVAILABILITY
Mduduzi Sithole, Final Submission Msc (M
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