03. January 2018

This investigation presents a study on the effect of various polymers on gelling properties of tri-block (Pluronic®) copolymers and increasing the stability parameter of in situ gelling system by altering their composition. The tri-block copolymers finds their importance in fabrication of in situ gelling system for the delivery of various kinds of drugs, which can be administered by topical, ophthalmic or parenteral routes.

12. December 2017

Development of sustained release formulations of Metformin hydrochloride (Met) having low bioavailability and short half-life is one of the frontier areas of research towards achieving novel drug delivery systems.

05. December 2017

The work is based on pulsatile principles to deliver a programmed dose of Irbesartan, an angiotensin-II receptor antagonist for chronotherapy of hypertension induced by excessive secretion of aldosterone, thereby lower the blood pressure at early morning. Solid dispersion of Irbesartan, a BCS class II drug, was prepared by using Poloxamer-188 by melt method in ratio of 1:1 to increase the dissolution properties of drug.

10. November 2017

Mucoadhesive formulations are well known for the delivery of drugs via the mucosal membrane of oral (sub- lingual, buccal and gingival), rectum, nose, eyes, and vagi- na. Among the various drug delivery approaches, the buc- cal mucosa delivery system o ers several bene ts like easy accessibility, patient compliance, a relatively large surface area of absorption for drug molecules, reduced gastric ir- ritation and simple delivery devices.