07. June 2018
Asthma is a chronic respiratory condition characterized by attacks of spasm in the bronchi of the lungs, causing difficulty in breathing. Oral and inhalation routes are generally used for the treatment of asthma. Terbutaline sulfate (TBS), is a widely used bronchodilator for the treatment of asthma, is available in formulations in the market. However, there is no commercially available orally disintegrating tablets (ODTs) containing TBS. Therefore, this study was aimed to develop and...
18. April 2016
In the present study an attempt has been made to evaluate Ocimum bascilium mucilage coprocessed with Mannitol as a novel super disintegrant. Coprocessed excipients were prepared by solvent evaporation method and evaluated in the formulation of mouth dissolving tablets of Terbutaline sulphate. Formulated mouth dissolving tablets were characterised for physicochemical parameters like hardness, friability, weight variation, disintegration time, drug content and in vitro drug release behaviour. The...