08. August 2018
Polymeric gels have emerged as promising vehicles for drug delivery across the skin. Stratum corneum, the topmost layer of the skin, does not allow hydrophilic and high molecular weight drugs to permeate without enhancing techniques. A number of enhancement techniques are being developed to increase the transdermal drug permeation. The transdermal route has many advantages and has therefore evolved as an attractive and convenient alternative to the existing routes of drug delivery that causes...
03. December 2017
The aims of this study are to prepare and characterize a microemulsion-based hydrogel containing celecoxib (CLX) for transdermal delivery. Pseudo-ternary phase diagrams containing 0.74% (w/w) CLX were constructed usingawater titration method. The mixture exhibiting the largest area of the microemulsionregion was selected. The effect of the ratio of oil to themixtureof surfactant and cosurfactant (O/Smix) on in vitro skin permeation was investigated. Attenuated total reflectance-Fourier...
16. March 2017
Abstract It is one of the best pharmaceutical dosage forms for those patients, they cannot take medicaments orally. Transdermal drug delivery system (TDDS) established itself as an integral part of novel drug delivery systems (NDDS). On the application of Transdermal patches, the delivery of the drug across dermis gives the systemic effect. TDDS is costly alternative to conventional formulation. It is also important due to its unique advantage. Controlled absorption, more uniform plasma levels,...
21. September 2016
ABSTRACT Transdermal patch is a medicated adhesive patch that is placed on the skin to deliver the drug through the skin in order to achieve systemic absorption of drug at a predetermined rate over a prolonged period of time. The amalgamation of polymer and pharmaceutical sciences led to the introduction of polymer in the design and development of drug delivery systems. Polymeric delivery systems are mainly intended to achieve controlled or sustained drug delivery. Polysaccharides fabricated...
15. May 2016
Transdermal spray offers numerous advantages over the other conventional transdermal drug delivery forms such as gel, ointment and patches, in terms of its cosmeceutical appearance, ready availability for application, flexibility in dosage design, less occurrence of skin irritation and faster drying rate from the application site due to the use of volatile solvent. However, compared to other transdermal drug delivery dosage forms, transdermal spray has the least and limited number of products...
10. November 2015
Transcutol® or diethylene glycol monoethyl ether is a liquid which has a long history of use in cosmetic and over-the-counter topically applied products. Transcutol® has been applied in several commercial preparations and is used in many studies as the main ingredient of formulations. It has been used in formulations as a co-surfactant and a penetration enhancer. More Book: Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement
07. June 2015
The aim of this study was to evaluate the capacity of cellulose films enriched with oleic acid and polysorbate 80 to enhance the transdermal permeation of propranolol hydrochloride. See more
04. February 2015
John B. Cannon, Ph.D. - Posted: December 01, 2014 http://www.americanpharmaceuticalreview.com/Featured-Articles/170872-Lipids-in-Transdermal-and-Topical-Drug-Delivery/?catid=6262