08. March 2016

In the pharmaceutical tablet film coating process, we clarified that a difference in exhaust air relative humidity can be used to detect differences in process parameters values, the relative humidity of exhaust air was different under different atmospheric air humidity conditions even though all setting values of the manufacturing process parameters were the same, and the water content of tablets was correlated with the exhaust air relative humidity. Based on this experimental data, the...

05. October 2015

Highlights •Alginate pellets are prepared by air-pressurized melt pelletization technique. •Melt pelletization is conducted in a high shear mixer. •Air-pressurized melt pellets exhibit slow drug release characteristics. •Pellet consolidation within short processing time sustains drug release. •Prolonged air bubbling induces porous core that fails to sustain drug release. More