Melt pelletization of alginate: Effects of air pressurization on consolidation and drug release property of pellets - Abstract

Highlights

•Alginate pellets are prepared by air-pressurized melt pelletization technique.

•Melt pelletization is conducted in a high shear mixer.

•Air-pressurized melt pellets exhibit slow drug release characteristics.

•Pellet consolidation within short processing time sustains drug release.

•Prolonged air bubbling induces porous core that fails to sustain drug release.

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