09. April 2018

Pharmaceutical powders can exhibit markedly different tablet ejection forces. The purpose of this study is to understand the factors leading to the variability of the tablet ejection force and its sensitivity to lubrication. The study showed that the tablet ejection force is mainly governed by 1) tablet diameter and thickness, 2) compact-die wall friction coefficient, and 3) residual die wall stress upon ejection; the latter was further controlled by the maximum compression pressure, as well as...

26. September 2017

The lubrication effects of two mixing systems were studied. Shear without MgSt significantly increased blend cohesion. The effect of shear rate during lubrication was not significant. The correlations between two mixing systems were established