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13. September 2016
ABSTRACT The crystallization of nonsteroidal anti-inflammatory drug [2-(4-isobutyl-phenyl) propionic acid] ibuprofen (IBP) on a hydroxypropyl cellulose (HPC) and polyacrylamide (PAAm) gel was studied as well as the release kinetics of the drug. The IBP was crystallized on the gel surface of HPC/PAAm, it had a prismatic shape and the growth was made in an aqueous medium, the crystallinity grade of the gel HPC/PAAm and HPC/PAAm-IBU were to 65 and 58. % respectively. The release of IBP is...