22. November 2017

Background and Objective: Single-unit solid oral dosage forms such as tablets and capsules are considered the most common and acceptable form of immediate release systemic drug delivery systems. On the other hand, multiple-unit pellet systems (MUPS) have in recent years become an important dosage form that offers various advantages over conventional single-unit solid oral dosage forms.

25. October 2017

Terahertz pulsed imaging (TPI) was applied to analyse the inner structure of multiple unit pellet system (MUPS) tablets. MUPS tablets containing different amounts of theophylline pellets coated with Eudragit® NE 30 D and with microcrystalline cellulose (MCC) as cushioning agent were analysed

11. October 2017

The objective of this study was to formulate, optimize and evaluate sustained release pellets of venlafaxine hydrochloride. Venlafaxine hydrochloride sustained release pellets were prepared by solution layering technique.

14. September 2017

Prof Martin Whitaker (The University of Sheffield) will present Infacort®: a PUMA success story at the 9th conference of the European Paediatric Formulation Initiative (EuPFI) in Warsaw (Poland) on Thursday 21st September 2017 at 12:25.

05. September 2017

Abstract There has been limited research done on the downstream processing of nanosuspensions into solid oral dosage forms. This paper demonstrates the bead layering process with a layering level at 150% and 240%, as well as the selection and justification of the outer phase excipients for tabletability and disintegrating properties. In a previous study, an itraconazole nanosuspension stabilised by SDS and HPMC E5 was layered onto sugar beads with coating polymer HPMC VLV. In the current study,...

23. August 2017

The multiparticulate drug product concept covering micropellets, pellets, and mini-tablets is presented as a highly feasible approach to present convenient and patient friendly medication for the geriatric population. Improved swallowability and optimized administration regimen going along with defined drug dosage are achievable.

27. July 2017

With the XStraw® drinking straw, a product innovation by the company DS-Technology GmbH, the intake of drugs is made incredibly easy and becomes more convenient for patients with swallowing difficulties and the elderly - because drinking with a straw is the most wonderful thing for little ones and grown-ups alike.

05. July 2017

Acid-labile drugs are easily degraded in acidic medium, which have been mainly formulated as enteric-coated dosage forms for oral administration. The objective of this study was to prepare oral multiparticulate formulations of acid-labile drugs, using ilaprazole, lansoprazole and rabeprazole sodium as model drugs.

29. June 2017

Process Analytical Technology, or "PAT" is the term given to analytical instruments developed to measure certain attributes of product within the manufacturing process, eliminating, or substantially minimising the need for sampling for off-line analysis

26. May 2017

During the Ramadan, Muslims fast every day, from dawn to sunset, for a whole month. The fast is a stressful period when individuals abstain from eating and drinking and are therefore at risk of dehydration, fainting, low glucose levels, intense thirst, and asthenia.